More than 99% of all bacteria live in biofilm communities and once embedded in the biofilm the bacteria are 100-1000 times more resistant to antibiotics, antimicrobials, biocides and the host immune system compared to their planktonic counterparts.
Biofilms can exist on all types of surfaces ranging from floors, walls, pipes and drains, and surfaces of equipment including stainless steel, aluminum, nylon, Teflon, rubber, plastic and glass. Two areas that Kane has explored are hard surface disinfectants and medical device coatings.
The United States Department of Agriculture (USDA) estimates the costs associated with food borne illness to be as high as $22 billion a year. This doesn’t include the billions lost every year due to spoiled product.
About 60-70% of hospital-acquired infections are associated with some type of implanted medical device. The worldwide production of biomedical devices is about $180 billion a year and expanding rapidly. All medical devices are susceptible to microbial colonization and infection as a result of biofilms.
“In work described in Antimicrobial Agents and Chemotherapy and the Journal of Industrial Microbiology and Biotechnology, researchers at Kane Biotech made therapeutic and analytical progress against biofilms, a particularly intractable form of bacterial growth.”
– Drug Discovery News.com
Medical Device Coating
Kane Biotech’s trademark for the medical device coating market is Aledex®. Kane has excellent data that demonstrates the product’s ability to inhibit the activity of numerous catheter associated pathogens, and protect against related infections. Approximately 30 million catheters are sold in North America annually. Indwelling urinary catheters are used in approximately 15% to 25% of short term care patients and in all patients in intensive care units. Additionally, in the US alone, more than 150 million intravascular catheters are used and over 5 million central venous lines are inserted. This results in about 250,000 catheter biofilm related infections each year.
Hard Surface Disinfectant
KBI contains a unique, patented, antimicrobial-antibiofilm combination comprised of Chlorhexidine (CHX) and Sodium Metaperiodate (SMP). CHX has broad-spectrum antimicrobial activity and SMP has broad-spectrum antipolysaccharide (biofilm) activity in addition to antimicrobial action.
How KBI works
- Breaks down the Polysaccharide (biofilm), exposing the bacteria
- Kills the now exposed bacteria with the antimicrobial agent
Disrupting the environment bacteria live in is critical in order to assure the embedded bacteria are killed.