To accelerate product research and development, whilst providing non-dilutive capital and opening new global markets.
Accelerating R&D and expanding geographies
Kane Biotech has been at the forefront for research and development to address the issues of Biofilms. The company has a portfolio of 52 patents and patents pending that has been created during the previous decade. As each solution has been proven via large scale trials the company is now focused on commercializing each product within defined consumer verticals. Whether you are a direct consumer, veterinarian or dermatologist Kane Biotech has a tried and tested solution; from our Animal Health products such as bluestem™ oral care to our first Human Health products such as DermaKB™ skin care. Kane Biotech’s commercialization vehicles will provide capital, at attractive valuations, that is non-dilutive to the company. This capital will accelerate our continued product research and development for the future whilst allowing our commercialization beyond North America.
STEM Animal Health
80% of dogs and 70% of cats will show some stage of gum disease by 3 years of age.
Kane’s 1st Commercialization Vehicle formed in partnership with Animalcare Group, STEM Animal Health is a new animal health company dedicated to targeting biofilm-related ailments. With a global oral care market valued at $5.2bn, the joint venture will allow STEM Animal Health to reach beyond North America and deliver products to companion animals in the global market.
In the new partnership, Kane Biotech maintains a 67% equity ownership in the company and provides administrative, R&D and product development services. With a CAD $5M investment into the company over 4 years, Animalcare Group assumes a 33% equity stake with an option to acquire an additional 17% for $4M payable to Kane.
The agreement will see Animalcare commercialize Kane Biotech’s range of oral care products for companion animals in European and Asian markets and collaborate with Kane Biotech on the development of new biofilm treatments for animals.
In 2020, Kane Biotech’s bluestem™ brand of pet oral care products contributed to STEM revenues of $2M. All bluestem™ products are scientifically formulated with our patented coactiv+™ technology to safely break down plaque and tartar biofilm and freshen breath. The product line includes a liquid water additive in 3 flavours (original, chicken and vanilla mint), oral spray, toothpaste in 2 flavours (chicken and vanilla mint, in packaging options that come with a toothbrush and without), powder water additive, dental wipes, dental chews, and rawhide dental chews.
Also under development for the pet specialty channel is a new pet skin care product under the silkstem™ brand. Although results from consumer testing in 2020 was overwhelmingly positive, it is STEM’s intention to make some minor improvements in both formulation and packaging in 2021.
Kane Wound Care & Surgical
The prevention and management of biofilm in chronic wounds has become a primary objective in wound care, with the presence of biofilm recognized as a leading cause of delayed wound healing.1-5
THE UNMET CLINICAL NEED – BIOFILM DISRUPTION
Biofilms are pervasive and represent the most prevalent bacterial mode of growth. The current wound care global market is expected to reach US $22bn by 2022. In order to meet growing needs and accelerate the development of it’s wound and surgical care technology portfolio, Kane Biotech has created a Wound Care & Surgical Commercialization Vehicle.
Kane will be submitting to the FDA a Pre-Market Application (PMA) for a DispersinB® Hydrogel as a medical device. Regulatory approval will trigger the development of further DispersinB® based technologies and products: dressings – antimicrobial, barrier, silicone, films and foam; skin cleansers and wipes; gauzes and bandages and pre- and post-surgical rinses. Potential indications include diabetic foot and leg ulcers, pressure ulcers (stage I-IV), partial & full thickness wounds, post-surgical wounds, and first & second-degree burns.
Kane will also be petitioning the FDA for regulatory approval for coactiv+™ under the 510(K) pathway as a line of medical devices for a variety of antibiofilm applications associated with chronic infections, infection prevention, chemical wound debridement and surgical washes.
Kane is actively seeking a strategic partner to support future commercialization of the DispersinB® Hydrogel, coactiv+™ and other product offerings in the wound care and surgical markets. Benefits of this partnership to a strategic organization would include:
- Access to the new and higher standard in effective Biofilm treatment with DispersinB® Hydrogel and exclusive worldwide commercialization rights
- Partnership with a financially strong Canadian biotech company with tenured executive management and experienced scientific teams
- A strong patent family allowing for global coverage for multiple applications
- The opportunity to position itself as THE “biofilm” company with transformational technologies and support from top industry scientists and research partners in the field
“For the 1st time in decades, this person shows NO signs of dandruff and seborrheic dermatitis at all. NONE! I would characterize this result as miraculous! This person has literally tried any and all products including prescription medications. This product you have developed is a GAMECHANGER. We are blown away by the results.”
– Managing Director, Large Investment Banking Firm
In keeping with Kane Biotech’s business model, the strategic focus of the Kane OTC subsidiary is to develop and sell non-prescription consumables to end customers that treat minor health ailments where biofilms contribute to the problem. These consumables will be premium products, non-antibiotic, and tested as safe for human use. They will not include any harsh chemicals and will be produced at a level of quality and efficacy to support recommendation by medical specialists such as Dermatologists and ENTs.
Kane OTC recently launched a shampoo, shampoo bar and scalp detoxifier under the DermaKB brand as the first products in their new skin care line. The products will be sold direct-to-consumer through Kane’s new online commerce site: www.dermakb.com.
The retail site offers several shampoo products that contain Kane Biotech’s proprietary patented coactiv+™ technology. The products are formulated to provide an effective cleansing of the scalp, helping support the reduction of skin irritation and other symptoms associated with common skin conditions. DermaKB™ Shampoo is available on the website in a 1000ml bottle as well as in a four-pack of 45g Shampoo Bars. Additionally, a 500ml bottle Scalp Detoxifier complements the product offering. The DermaKB™ product line is purposely unscented to avoid any further irritants for the consumer.
Other products currently under development include a nasal spray for chronic sinusitis.